Lifestyle and gout

被引:51
作者
Hak, A. Elisabeth [2 ,3 ,4 ]
Choi, Hyon K. [1 ,4 ,5 ]
机构
[1] Univ British Columbia, Dept Med, Vancouver Gen Hosp,Div Rheumatol, Arthritis Res Ctr, Vancouver, BC V5Z 1L7, Canada
[2] Erasmus MC Univ, Dept Rheumatol & Internal Med, Med Ctr, Rotterdam, Netherlands
[3] Brigham & Womens Hosp, Dept Med, Sect Clin Sci, Div Rheumatol Allergy & Immunol, Boston, MA 02115 USA
[4] Harvard Univ, Sch Med, Dept Med, Brigham & Womens Hosp,Channing Lab, Boston, MA USA
[5] Univ British Columbia, Vancouver Gen Hosp, Arthritis Res Ctr, Vancouver, BC V5Z 1M9, Canada
关键词
cardiovascular disease; comorbidity; diet; epidemiology; gout; lifestyle;
D O I
10.1097/BOR.0b013e3282f524a2
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of review This review summarizes recent epidemiologic research findings on gout, and attempts to put them into the context of clinical and public health decision-making aimed at prevention and improved management of gout. Recent findings A large prospective study found that coffee consumption was inversely associated with risk of gout and that consumption of sugar-sweetened soft drinks or fructose was strongly associated with an increased gout risk. Studies based on the Third National Health and Nutrition Examination Survey (NHANES III) suggest that these consumptions affect serum uric acid levels parallel to the direction of gout risk. Furthermore, data from NHANES III show a remarkably high prevalence of the metabolic syndrome among individuals with gout. Prospective studies found an increased risk of myocardial infarction and cardiovascular mortality in gout patients. Summary Lifestyle and dietary recommendations for gout patients should consider other health benefits, since gout is often associated with major chronic disorders such as the metabolic syndrome and an increased risk for cardiovascular disease and mortality. In addition to recent dietary recommendations, gout patients should be advised to limit fructose intake. The inverse link between coffee and the risk of gout suggests that coffee could be allowed among gout patients.
引用
收藏
页码:179 / 186
页数:8
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