Expression of agouti-related peptide, neuropeptide Y, pro-opiomelanocortin and the leptin receptor isoforms in fetal mouse brain from pregnant dams on a protein-restricted diet

被引:22
作者
Terroni, PL [1 ]
Anthony, FW [1 ]
Hanson, MA [1 ]
Cagampang, FRA [1 ]
机构
[1] Univ Southampton, Ctr Dev Origins Hlth & Dis, Sch Med, Princess Anne Hosp, Southampton SO16 5YA, Hants, England
来源
MOLECULAR BRAIN RESEARCH | 2005年 / 140卷 / 1-2期
关键词
NPY; POMC; AgRP; leptin receptor; fetal brain;
D O I
10.1016/j.molbrainres.2005.07.002
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Expression of agouti-related peptide, neuropeptide Y, pro-opiomelanocortin and leptin receptor isoforms were found in fetal mouse brain at embryonic day 12 (E12). Levels of expression for these genes were altered in brains of E12 fetuses from pregnant dams on a protein-restricted diet, suggesting that the fetal brain is responsive to changes in maternal nutrition prior to birth. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码:111 / 115
页数:5
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