Kinesins and protein kinases: Key players in the regulation of microtubule dynamics and organization

被引：31

作者：

Daire, Vanessa ^{[1
]}

Poues, Christian ^{[1
,2
]}

机构：

[1] Univ Paris 11, UPRES EA 4530, Fac Pharm, F-92296 Chatenay Malabry, France

[2] Hop Antoine Beclere, AP HP, F-92141 Clamart, France

来源：

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 2011年 / 510卷 / 02期

关键词：

Kinesin; Microtubule dynamics; Protein kinase; Cellular signaling; Mitotic spindle; Cilium; TUMOR-SUPPRESSOR PROTEIN; CENTROMERE-ASSOCIATED KINESIN; BIPOLAR SPINDLE FORMATION; KIN-I KINESIN; MINUS-END; MITOTIC SPINDLE; MOTOR PROTEINS; AURORA-B; PLUS-END; DEPENDENT PHOSPHORYLATION;

D O I：

10.1016/j.abb.2011.02.012

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Microtubule dynamics is controlled and amplified in vivo by complex sets of regulators. Among these regulatory proteins, molecular motors from the kinesin superfamily are taking an increasing importance. Here we review how microtubule disassembly or assembly into interphase microtubules, mitotic spindle or cilia may involve kinesins and how protein kinases may participate in these kinesin-dependent regulations. (C) 2011 Elsevier Inc. All rights reserved.

引用

页码：83 / 92

页数：10

共 165 条

[1] Aurora B regulates MCAK at the mitotic centromere [J].

Andrews, PD ;

Ovechkina, Y ;

Morrice, N ;

Wagenbach, M ;

Duncan, K ;

Wordeman, L ;

Swedlow, JR .

DEVELOPMENTAL CELL, 2004, 6 (02) :253-268

[2] Adenomatous polyposis coli associates with the microtubule-destabilizing protein XMCAK [J].

Banks, JD ;

Heald, R .

CURRENT BIOLOGY, 2004, 14 (22) :2033-2038

[3] Phosphorylation of microtubule-associated protein STOP by calmodulin kinase II [J].

Baratier, Julie ;

Peris, Leticia ;

Brocard, Jacques ;

Gory-Faure, Sylvie ;

Dufour, Fabrice ;

Bosc, Christophe ;

Fourest-Lieuvin, Anne ;

Blanchoin, Laurent ;

Salin, Paul ;

Job, Didier ;

Andrieux, Annie .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (28) :19561-19569

[4] Polo-like kinases and the orchestration of cell division [J].

Barr, FA ;

Silljé, HHW ;

Nigg, EA .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2004, 5 (06) :429-440

[5] Phosphorylation by p34(cdc2) regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo [J].

Blangy, A ;

Lane, HA ;

dHerin, P ;

Harper, M ;

Kress, M ;

Nigg, EA .

CELL, 1995, 83 (07) :1159-1169

[6] Kinesin-dependent axonal transport is mediated by the Sunday driver (SYD) protein [J].

Bowman, AB ;

Kamal, A ;

Ritchings, BW ;

Philp, AV ;

McGrail, M ;

Gindhart, JG ;

Goldstein, LSB .

CELL, 2000, 103 (04) :583-594

[7] The kinesin-14 Klp2 organizes microtubules into parallel bundles by an ATP-dependent sorting mechanism [J].

Braun, Marcus ;

Drummond, Douglas R. ;

Cross, Robert A. ;

McAinsh, Andrew D. .

NATURE CELL BIOLOGY, 2009, 11 (06) :724-U55

[8] Tea2p kinesin is involved in spatial microtubule organization by transporting Tip1p on microtubules [J].

Busch, KE ;

Hayles, J ;

Nurse, P ;

Brunner, D .

DEVELOPMENTAL CELL, 2004, 6 (06) :831-843

[9] Poleward tubulin flux in spindles: Regulation and function in mitotic cells [J].

Buster, Daniel W. ;

Zhang, Dong ;

Sharp, David J. .

MOLECULAR BIOLOGY OF THE CELL, 2007, 18 (08) :3094-3104

[10] Kinesin-14 Family Proteins HSET/XCTK2 Control Spindle Length by Cross-Linking and Sliding Microtubules [J].

Cai, Shang ;

Weaver, Lesley N. ;

Ems-McClung, Stephanie C. ;

Walczak, Claire E. .

MOLECULAR BIOLOGY OF THE CELL, 2009, 20 (05) :1348-1359

← 1 2 3 4 5 6 7 8 9 10 →