Databases and software for the comparison of prokaryotic genomes

被引:14
作者
Field, D
Feil, EJ
Wilson, GA
机构
[1] Oxford Ctr Ecol & Hydrol, Oxford OX1 3SR, England
[2] Univ Bath, Dept Biol & Biochem, Bath BA2 7AY, Avon, England
来源
MICROBIOLOGY-SGM | 2005年 / 151卷
关键词
D O I
10.1099/mic.0.28006-0
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The explosion in the number of complete genomes over the past decade has spawned a new and exciting discipline, that of comparative genomics. To exploit the full potential of this approach requires the development of novel algorithms, databases and software which are sophisticated enough to draw meaningful comparisons between complete genome sequences and are widely accessible to the scientific community at large. This article reviews progress towards the development of computational tools and databases for organizing and extracting biological meaning from the comparison of large collections of genomes.
引用
收藏
页码:2125 / 2132
页数:8
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