Design, synthesis and cleaving activity of an abiotic nuclease based on a manganese(III) porphyrin complex bearing two acridine moieties

被引：12

作者：

Drexler, C

Hosseini, MW ^{[1
]}

Pratviel, G

Meunier, B

机构：

[1] Univ Louis Pasteur, Chim Coordinat Organ Lab, F-67000 Strasbourg, France

[2] CNRS, Chim Coordinat Lab, F-31077 Toulouse 4, France

来源：

CHEMICAL COMMUNICATIONS | 1998年 / 13期

关键词：

D O I：

10.1039/a801095a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis of meso-5,15-bis(m-aminophenyl)porphyrin bearing two acridine derivatives and of its manganese(III) complex was achieved; in the presence of oxygen atom donors, the metalloporphyrin was shown to cleave double-stranded DNA.

引用

页码：1343 / 1344

页数：2

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