Influence of ionic substitution in improving the biological property of carbon nanotubes reinforced hydroxyapatite composite coating on titanium for orthopedic applications

被引：57

作者：

Gopi, D. ^{[1
,2
]}

Shinyjoy, E. ^{[1
]}

Kavitha, L. ^{[3
]}

机构：

[1] Periyar Univ, Dept Chem, Salem 636011, Tamil Nadu, India

[2] Periyar Univ, Ctr Nanosci & Nanotechnol, Salem 636011, Tamil Nadu, India

[3] Cent Univ Tamilnadu, Sch Basic & Appl Sci, Dept Phys, Thiruvarur 610101, Tamil Nadu, India

来源：

CERAMICS INTERNATIONAL | 2015年 / 41卷 / 04期

关键词：

Composites; Spectroscopy; Carbon; Biomedical applications; GRADE STAINLESS-STEEL; IN-VITRO; BIOMEDICAL APPLICATIONS; CORROSION-RESISTANCE; STRONTIUM; MAGNESIUM; ZINC; NANOPARTICLES; DEPOSITION; ELECTRODEPOSITION;

D O I：

10.1016/j.ceramint.2014.12.114

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

081705 [工业催化]; 082905 [生物质能源与材料];

摘要：

The present work is aimed for the development of carbon nanotubes (CNTs) reinforced single mineral (Sr, Mg, Zn) as well as multi minerals (Sr+Mg+Zn) substituted hydroxyapatite composite (M-HAP) coatings on titanium (Ti). The effect of different mineral ions substitution and CNTs reinforcement in HAP composite coating is discussed in detail. Fourier Transform Infrared spectroscopy (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM) equipped with energy dispersive X-ray analysis (EDX), and high resolution transmission electron microscopy (HRTEM) were used to characterize the structural and morphological behavior of the composite coatings. The corrosion resistance of the composite coatings in simulated body fluid (SBF) solution was evaluated by the potentiodynamic polarization and electrochemical impedance spectroscopic (EIS) studies. In addition, the biocompatibility of the composite coatings was evaluated by in vitro culture of human osteoblast MG63 cells on the-composite coated Ti. All these results essentially suggest that CNTs/M-HAP composite coated Ti can be a potential candidate for orthopedic applications. (C) 2014 Elsevier Ltd and Techna Group S.r.l. All rights reserved.

引用

页码：5454 / 5463

页数：10

共 34 条

[1]

Magnesium- and strontium-co-substituted hydroxyapatite: the effects of doped-ions on the structure and chemico-physical properties [J].

Aina, Valentina ;

Lusvardi, Gigliola ;

Annaz, Basil ;

Gibson, Iain R. ;

Imrie, Flora E. ;

Malavasi, Gianluca ;

Menabue, Ledi ;

Cerrato, Giuseppina ;

Martra, Gianmario .

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2012, 23 (12) :2867-2879

[2]

In vitro corrosion resistance of titanium made using different fabrication methods [J].

Cai, Z ;

Nakajima, H ;

Woldu, M ;

Berglund, A ;

Bergman, M ;

Okabe, T .

BIOMATERIALS, 1999, 20 (02) :183-190

[3]

Strontium-substituted hydroxyapatite coatings synthesized by pulsed-laser deposition: In vitro osteoblast and osteoclast response [J].

Capuccini, C. ;

Torricelli, P. ;

Sima, F. ;

Boanini, E. ;

Ristoscu, C. ;

Bracci, B. ;

Socol, G. ;

Fini, M. ;

Mihailescu, I. N. ;

Bigi, A. .

ACTA BIOMATERIALIA, 2008, 4 (06) :1885-1893

[4]

Composite calcium phosphate coatings with sustained Zn release [J].

Cheng, Kui ;

Zhou, Jiabei ;

Weng, Wenjian ;

Zhang, Sam ;

Shen, Ge ;

Du, Piyi ;

Han, Gaorong .

THIN SOLID FILMS, 2011, 519 (15) :4647-4651

[5]

Structural characterization of hydroxyapatite layer coatings on titanium supports [J].

Ciobanu, Gabriela ;

Carja, Gabriela ;

Ciobanu, Octavian .

SURFACE & COATINGS TECHNOLOGY, 2008, 202 (11) :2467-2470

[6]

The effect of moderately and severely restricted dietary magnesium intakes on bone composition and bone metabolism in the rat [J].

Creedon, A ;

Flynn, A ;

Cashman, K .

BRITISH JOURNAL OF NUTRITION, 1999, 82 (01) :63-71

[7]

The antimicrobial sensitivity of Streptococcus mutans to nanoparticles of silver, zinc oxide, and gold [J].

Francisco Hernandez-Sierra, Juan ;

Ruiz, Facundo ;

Cruz Pena, Diana Corina ;

Martinez-Gutierrez, Fidel ;

Emilio Martinez, Alberto ;

Pozos Guillen, Amaury de Jesus ;

Tapia-Perez, Humberto ;

Martinez-Castanon, Gabriel-Alejandro .

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2008, 4 (03) :237-240

[8]

Preparation and characterization of magnesium/carbonate co-substituted hydroxyapatites [J].

Gibson, IR ;

Bonfield, W .

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2002, 13 (07) :685-693

[9]

Strontium, cerium co-substituted hydroxyapatite nanoparticles: Synthesis, characterization, antibacterial activity towards prokaryotic strains and in vitro studies [J].

Gopi, D. ;

Ramya, S. ;

Rajeswari, D. ;

Karthikeyan, P. ;

Kavitha, L. .

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2014, 451 :172-180

[10]

Synthesis and spectral characterization of silver/magnesium co-substituted hydroxyapatite for biomedical applications [J].

Gopi, D. ;

Shinyjoy, E. ;

Kavitha, L. .

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2014, 127 :286-291

← 1 2 3 4 →