A guide to planning and executing a surgical randomized controlled trial

被引：13

作者：

Chung, Kevin C. ^{[1
]}

Burns, Patricia B. ^{[1
]}

机构：

[1] Univ Michigan Hlth Syst, Dept Surg, Sect Plast Surg, Ann Arbor, MI 48109 USA

来源：

JOURNAL OF HAND SURGERY-AMERICAN VOLUME | 2008年 / 33A卷 / 03期

关键词：

clinical trials; guide; surgery;

D O I：

10.1016/j.jhsa.2007.11.027

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Evidence-based medicine requires that treatments given to patients demonstrate effectiveness. The randomized controlled trial (RCT) has become the preeminent study design to assess the efficacy of treatments. Randomized controlled trials are frequently used to evaluate pharmaceutical treatments but are less often used in surgery. The lack of surgical RCTs is partly due to ethical and methodological concerns associated with surgical interventions. We provide a guide to planning and conducting a surgical RCT.

引用

页码：407 / 412

页数：6

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