Tracing Cells for Tracking Cell Lineage and Clonal Behavior

被引:103
作者
Buckingham, Margaret E. [1 ]
Meilhac, Sigolene M. [1 ]
机构
[1] Inst Pasteur, Mol Genet Dev Unit, CNRS URA 2578, Dept Dev Biol, F-75015 Paris, France
关键词
SITE-SPECIFIC RECOMBINATION; CENTRAL-NERVOUS-SYSTEM; FLUORESCENT PROTEINS; GENE-EXPRESSION; MOUSE EMBRYO; MOSAIC ANALYSIS; STEM-CELLS; HOMOLOGOUS RECOMBINATION; DROSOPHILA-MELANOGASTER; INTRACELLULAR INJECTION;
D O I
10.1016/j.devcel.2011.07.019
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Reconstructing the lineage of cells is central to understanding development and is now also an important issue in stem cell research. Technological advances in genetically engineered permanent cell labeling, together with a multiplicity of fluorescent markers and sophisticated imaging, open new possibilities for prospective and retrospective clonal analysis.
引用
收藏
页码:394 / 409
页数:16
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