Transition metal ion-catalyzed oxygen activation during pathogenic processes

被引：116

作者：

Hippeli, S ^{[1
]}

Elstner, EF ^{[1
]}

机构：

[1] Tech Univ Munich, Lehrstuhl Phytopathol, Lab Angew Biochem, D-85350 Freising Weihenstephan, Germany

来源：

FEBS LETTERS | 1999年 / 443卷 / 01期

关键词：

transition metal ion; reactive oxygen species; radical chain reaction; disease;

D O I：

10.1016/S0014-5793(98)01665-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Most pathological processes include the production of activated oxygen species augmented or attenuated by transition metal ions catalyzing one electron transitions. Inhalation of airborne particles, infections, ingestion of toxins or liberation from endogenous stores represent biological pathways for the induction of pathogenic processes by these metal ions, In this short review basic reactions involving transition metal ions operating during oxidative stress in certain diseases will be discussed. (C) 1999 Federation of European Biochemical Societies.

引用

页码：1 / 7

页数：7

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