Reflux in young patients: Comparison of voiding US of the bladder and retrovesical space with echo enhancement versus voiding cystourethrography for diagnosis

被引:139
作者
Darge, K
Troeger, J
Duetting, T
Zieger, B
Rohrschneider, W
Moehring, K
Weber, C
Toenshoff, B
机构
[1] Univ Heidelberg Hosp, Dept Pediat Radiol, D-69120 Heidelberg, Germany
[2] Univ Heidelberg Hosp, Div Pediat Nephrol, D-69120 Heidelberg, Germany
关键词
bladder; US; ultrasound; (US); contrast media; ureter; reflux; voiding cystourethrography;
D O I
10.1148/radiology.210.1.r99ja40201
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
PURPOSE: To compare the usefulness of voiding US of the bladder and retrovesical space with echo enhancement with that of voiding cystourethrography (VCUG) for diagnosis of vesicoureteral reflux (VUR) and to assess patient tolerance of the echo-enhancing agent. MATERIALS AND METHODS: One hundred eighty-eight patients (aged 5 days to 20 years) referred for investigation of VUR underwent voiding US with echo enhancement, which was followed by VCUG in 100 patients (226 kidney-ureter units). After US of the renal tract, the bladder was filled with normal saline solution. Then SH U 508 A, a galactose-based, microbubble-containing echo-enhancing agent, was administered. Reflux was diagnosed when microbubbles appeared in the ureter or pelvicalyceal system. RESULTS: VUR was detected in 80 of the units with one (n = 18) or both (n = 62) methods. All grades of reflux were identified. In 15 units, reflux diagnosed avoiding US was not observed at VCUG; the reverse was true in three units. In 208 (92%) of the 226 kidney-ureter units, there was concordance between the two methods regarding the diagnosis or exclusion of VUR. The echo-enhancing agent was well tolerated. CONCLUSION: SH U 508 A enhanced voiding US is as good VCUG in the detection or exclusion of VUR and thus will make it possible to reduce the number of children having to be exposed to ionizing radiation.
引用
收藏
页码:201 / 207
页数:7
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