Screening the PRF1, UNC13D, STX11, SH2D1A, XIAP, and ITK gene mutations in Chinese children with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis

被引：34

作者：

Huang Zhizhuo ^{[2
]}

Xu Junmei ^{[2
]}

Shen Yuelin ^{[2
]}

Qin Qiang ^{[2
]}

Liu Chunyan ^{[2
]}

Xie Zhengde ^{[2
]}

Shen Kunling ^{[1
]}

机构：

[1] Capital Med Univ, Beijing Childrens Hosp, Dept Infect, Beijing 100045, Peoples R China

[2] Capital Med Univ, Beijing Childrens Hosp, Dept Virol Lab, Beijing 100045, Peoples R China

来源：

PEDIATRIC BLOOD & CANCER | 2012年 / 58卷 / 03期

关键词：

primary hemophagocytic lymphohistiocytosis; Epstein-Barr virus; gene mutation; PRF1; UNC13D; STX11; SH2D1A; XIAP; ITK; LINKED LYMPHOPROLIFERATIVE DISEASE; PERFORIN GENE; EBV INFECTION; IDENTIFICATION; SUSCEPTIBILITY; DEFICIENCY; MUNC13-4; LINKAGE;

D O I：

10.1002/pbc.23216

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Background This study aimed to investigate the prevalence of mutations in the PRF1, UNC13D, STX11, SH2D1A, XIAP, and ITK in Chinese pediatric patients with EBV-HLH.

引用

页码：410 / 414

页数：5

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