Mucosal exposure to light during routine endoscopy

被引:3
作者
Nishioka, NS
Schomacker, KT
机构
[1] Massachusetts Gen Hosp, Med Serv, Boston, MA 02114 USA
[2] Massachusetts Gen Hosp, Gastrointestinal Unit, Boston, MA 02114 USA
[3] Massachusetts Gen Hosp, Wellman Labs Photomed, Boston, MA 02114 USA
[4] Harvard Univ, Sch Med, Dept Med, Boston, MA USA
[5] Harvard Univ, Sch Med, Dept Dermatol, Boston, MA 02115 USA
关键词
D O I
10.1016/S0016-5107(99)70042-8
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background: The spectral irradiance delivered by a variety of gastrointestinal endoscopes was measured as a function of wavelength and used to estimate the amount of light delivered to the mucosal surface during routine endoscopic procedures. Methods: Spectral irradiances from seven different endoscopes were measured using a commercial spectroradiometer calibrated against a National Institute of Standards and Technology traceable source. Results: The largest maximum irradiance was 8.0 W/cm(2) obtained from an endoscope used in transillumination mode. In the typical viewing mode, the largest maximum irradiance measured was 1.6 W/cm(2). The majority of the light energy delivered by these gastrointestinal endoscopes was in the visible wavelength region (400 to 700 nm), Discussion: The measurements revealed surprisingly high light exposures in the visible wavelength range. In fact, the estimated tissue exposures can exceed by 40-fold the standards established for skin exposure to light set forth by the American National Standards Institute. Because gastrointestinal endoscopy is widely viewed to be safe, it is probable that the gastrointestinal tract has significant tolerance to light exposure.
引用
收藏
页码:456 / 461
页数:6
相关论文
共 14 条
[1]  
*AM NAT STAND COMM, 1993, Z13611993 ANSI LAS I, P71
[2]   Safety analysis: Relative risks of ultraviolet exposure from fluorescence spectroscopy and colposcopy are comparable [J].
Brookner, CK ;
Agrawal, A ;
Trujillo, EV ;
Mitchell, MF ;
RichardsKortum, RR .
PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1997, 65 (06) :1020-1025
[3]   Detection of dysplasia at colonoscopy using laser-induced fluorescence: A blinded study [J].
Cothren, RM ;
Sivak, MV ;
VanDam, J ;
Petras, RE ;
Fitzmaurice, M ;
Crawford, JM ;
Wu, J ;
Brennan, JF ;
Rava, RP ;
Manoharan, R ;
Feld, MS .
GASTROINTESTINAL ENDOSCOPY, 1996, 44 (02) :168-176
[4]   GASTROINTESTINAL TISSUE DIAGNOSIS BY LASER-INDUCED FLUORESCENCE SPECTROSCOPY AT ENDOSCOPY [J].
COTHREN, RM ;
RICHARDSKORTUM, R ;
SIVAK, MV ;
FITZMAURICE, M ;
RAVA, RP ;
BOYCE, GA ;
DOXTADER, M ;
BLACKMAN, R ;
IVANC, TB ;
HAYES, GB ;
FELD, MS ;
PETRAS, RE .
GASTROINTESTINAL ENDOSCOPY, 1990, 36 (02) :105-111
[5]   MUTAGENESIS AND CYTOTOXICITY IN HUMAN EPITHELIAL-CELLS BY FAR-ULTRAVIOLET AND NEAR-ULTRAVIOLET RADIATIONS - ACTION SPECTRA [J].
JONES, CA ;
HUBERMAN, E ;
CUNNINGHAM, ML ;
PEAK, MJ .
RADIATION RESEARCH, 1987, 110 (02) :244-254
[6]   LASER-INDUCED FLUORESCENCE SPECTROSCOPY OF HUMAN COLONIC MUCOSA - DETECTION OF ADENOMATOUS TRANSFORMATION [J].
KAPADIA, CR ;
CUTRUZZOLA, FW ;
OBRIEN, KM ;
STETZ, ML ;
ENRIQUEZ, R ;
DECKELBAUM, LI .
GASTROENTEROLOGY, 1990, 99 (01) :150-157
[7]   CYTO-TOXICITY AND MUTAGENICITY OF EXCIMER LASER-RADIATION [J].
KOCHEVAR, IE .
LASERS IN SURGERY AND MEDICINE, 1989, 9 (05) :440-445
[8]   LIGHT-INDUCED FLUORESCENCE SPECTROSCOPY OF ADENOMAS, ADENOCARCINOMAS AND NONNEOPLASTIC MUCOSA IN HUMAN COLON .1. INVITRO MEASUREMENTS [J].
MARCHESINI, R ;
BRAMBILLA, M ;
PIGNOLI, E ;
BOTTIROLI, G ;
CROCE, AC ;
DALFANTE, M ;
SPINELLI, P ;
DIPALMA, S .
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 1992, 14 (03) :219-230
[9]  
MORITZ AR, 1947, AM J PATHOL, V23, P695
[10]  
SCHOMACKER KT, 1992, GASTROENTEROLOGY, V102, P1155