Shared principles in NF-κB signaling

被引：5755

作者：

Hayden, Matthew S. ^{[1
]}

Ghosh, Sankar ^{[1
,2
]}

机构：

[1] Yale Univ, Sch Med, Dept Immunobiol, New Haven, CT 06510 USA

[2] Yale Univ, Sch Med, Dept Mol Biophys & Biochem, New Haven, CT 06510 USA

来源：

CELL | 2008年 / 132卷 / 03期

关键词：

D O I：

10.1016/j.cell.2008.01.020

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

The transcription factor NF-kappa B has served as a standard for inducible transcription factors for more than 20 years. The numerous stimuli that activate NF-kappa B, and the large number of genes regulated by NF-kappa B, ensure that this transcription factor is still the subject of intense research. Here, we attempt to synthesize some of the basic principles that have emerged from studies of NF-kappa B, and we aim to generate a more unified view of NF-kappa B regulation.

引用

页码：344 / 362

页数：19

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