SarA of Staphylococcus aureus binds to the sarA promoter to regulate gene expression

被引：35

作者：

Cheung, Ambrose L. ^{[1
]}

Nishina, Koren

Manna, Adhar C. ^{[2
]}

机构：

[1] Dartmouth Med Sch, Dept Microbiol & Immunol, Hanover, NH 03766 USA

[2] Univ S Dakota, Sanford Sch Med, Div Basic Biomed Sci, Vermillion, SD 57069 USA

来源：

JOURNAL OF BACTERIOLOGY | 2008年 / 190卷 / 06期

关键词：

D O I：

10.1128/JB.01826-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The 375-by sarA open reading frame is driven by three promoters, P1, P3, and P2. Using gel shift and DNase I footprinting assays, we found that SarA binds to two 26-bp sequences and one 31-bp sequence within the P1 and P3 promoters, respectively. Together with the results of transcription analyses, our data indicate that SarA binds to its own promoter to down-regulate sarA expression.

引用

页码：2239 / 2243

页数：5

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