Differences in composition and mucosal adhesion of bifidobacteria isolated from healthy adults and healthy seniors

被引：109

作者：

He, F

Ouwehand, AC ^{[1
]}

Isolauri, E

Hosoda, M

Benno, Y

Salminen, S

机构：

[1] Univ Turku, Dept Biochem & Food Chem, FIN-20014 Turku, Finland

[2] Takanashi Milk Prod Co Ltd, Tech Res Lab, Yokohama, Kanagawa 2410023, Japan

[3] Turku Univ, Cent Hosp, Dept Paediat, FIN-20521 Turku, Finland

[4] Inst Phys & Chem Res, RIKEN, Japan Collect Microorganisms, Wako, Saitama 35101, Japan

来源：

CURRENT MICROBIOLOGY | 2001年 / 43卷 / 05期

关键词：

D O I：

10.1007/s002840010315

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Fifty-one Bifidobacterium strains were isolated from the feces of healthy adults (30-40 years old) and seniors (older than 70 years of age). B. adolescentis, B. breve, B. infantis, and B. longum were isolated from the healthy adults and B. adolescentis and B. longum from elderly subjects. The tested bacteria bound, in vitro, to intestinal mucus in a strain dependent manner. The strains isolated from healthy adults, and especially B. adolescentis, bound better to intestinal mucus than those isolated from seniors. These results indicate that the mucosal adhesive properties of the human Bifidobacterium flora were reduced with the aging of the host. This shift to a Bifidobacterium flora with reduced adhesive abilities may explain the decrease in bifidobacteria levels in the intestinal microflora of aging people.

引用

页码：351 / 354

页数：4

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