A comparison of three measures: the time trade-off technique, global health-related quality of life and the SF-36 in dialysis patients

被引:32
作者
Maor, Y [1 ]
King, M [1 ]
Olmer, L [1 ]
Mozes, B [1 ]
机构
[1] Tel Aviv Univ, Sheba Med Ctr, Sackler Sch Med,Gertner Inst Epidemiol & Hlth Pol, Ctr Study Clin Reasoning, IL-52621 Tel Hashomer, Israel
关键词
utility; time trade-off; quality of life; SF-36; global measure; end stage renal disease;
D O I
10.1016/S0895-4356(00)00338-3
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
We investigated the correlation between descriptive and valuational measures of health-related quality of life (HRQL) and assessed determinants affecting these measures. Our suspicion was that there is little similarity in the content of descriptive and valuational measures of HRQL. We thus conducted a cross-sectional observational study of 56 hemodialysis patients. All underwent structured interviews. Dependent variables were patients utilities [time trade-off (TTO)], global rating of HRQL and generic HRQL (SF-36). Independent variables were socioeconomic details, disease severity, comorbidity, symptoms, depression, social support, and laboratory data. The correlation between TTO and global HRQL was -0.33 (P = .0178) and between TTO and the SF-36 physical and mental summary scores -0.16 (P = .2383) and -0.20 (P = .1443), respectively. The regression models for the SF-36 physical and mental summary scores explained 75% and 64% of the variance, and for global HRQL 29% of the variance. The independent variables had no effect on the TTO. This confirmed our suspicion that a qualitative difference exists between TTO and descriptive quality of life tools. The TTO content could not be explained by the variables that entail the content of HRQL instruments. (C) 2001 Elsevier Science Inc. All rights reserved.
引用
收藏
页码:565 / 570
页数:6
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