Poor postoperative blood glucose control increases surgical site infections after surgery for hepato-biliary-pancreatic cancer: a prospective study in a high-volume institute in Japan

被引：86

作者：

Ambiru, S. ^{[1
,2
]}

Kato, A. ^{[1
]}

Kimura, F. ^{[1
]}

Shimizu, H. ^{[1
]}

Yoshidome, H. ^{[1
]}

Otsuka, M. ^{[1
]}

Miyazaki, M. ^{[1
]}

机构：

[1] Chiba Univ, Grad Sch Med, Dept Gen Surg, Chuo Ku, Chiba 2608677, Japan

[2] Chiba Univ Hosp, Surg Ctr, Chuo Ku, Chiba 2608677, Japan

来源：

JOURNAL OF HOSPITAL INFECTION | 2008年 / 68卷 / 03期

关键词：

surgical site infection; hepato-biliary-pancreatic surgery; blood glucose control;

D O I：

10.1016/j.jhin.2007.12.002

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Two hundred and sixty-five consecutive patients awaiting hepato-biliary-pancreatic surgery were prospectively observed for surgical site infections (SSIs). SSI rates differed according to type of hepato-biliary-pancreatic surgery. Multivariate analysis identified enteric anastomoses, poor postoperative blood glucose control and type of cancer as independent risk factors. SSI rates were directly correlated with the degree of hyperglycaemia encountered during the postoperative period. In particular, SSI rates were 5/25 (20%) among patients in whom a blood glucose level of < 200 mg/dL was maintained by insulin infusion therapy, which was significantly better than the rates of 49/94 (52%) among patients in whom a blood glucose level of < 200 mg/dL was not maintained despite insulin infusion therapy (P < 0.01). It is necessary to maintain postoperative blood glucose levels of < 200 mg/dL in order to reduce SSI rates. (c) 2008 The Hospital Infection Society. Published by Elsevier Ltd. All rights reserved.

引用

页码：230 / 233

页数：4

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