Satisfaction after contralateral prophylactic mastectomy: The significance of mastectomy type, reconstructive complications, and body appearance

被引:156
作者
Frost, MH
Slezak, JM
Tran, NV
Williams, CI
Johnson, JL
Woods, JE
Petty, PM
Donohue, JH
Grant, CS
Sloan, JA
Sellers, TA
Hartmann, LC
机构
[1] Mayo Clin, Div Med Oncol, Rochester, MN 55905 USA
[2] Mayo Clin, Div Stat, Rochester, MN 55905 USA
[3] Mayo Clin, Div Plast & Reconstruct Surg, Rochester, MN 55905 USA
[4] Mayo Clin, Div Internal Med, Rochester, MN 55905 USA
[5] Mayo Clin, Div Surg & Surg Specialities, Rochester, MN 55905 USA
[6] H Lee Moffitt Canc Ctr & Res Inst, Div Canc Prevent & Control, Tampa, FL USA
关键词
D O I
10.1200/JCO.2005.09.233
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
Purpose Contralateral prophylactic mastectomy (CPM) is one option for reducing the risk of a second breast cancer in women with a personal and family history of breast cancer. Few data are available regarding satisfaction, psychological, and social function after CPM. The purpose of this research is to evaluate women's long-term satisfaction with CPM, factors influencing satisfaction, and psychological and social function after CPM. Patients and Methods This was a descriptive study of all women with a family history of breast cancer, known to be alive, who elected CPM at Mayo Clinic (Rochester, MN) between 1960 and 1993 (n = 621). Ninety-four percent of the women (n = 583) completed a study-specific questionnaire. Results A mean of 10.3 years after the procedure, the majority of women (83%) were satisfied with their CPM. A smaller number were neutral (8%) or dissatisfied (9%). Women who had a subcutaneous mastectomy had more problems with reconstruction, and fewer of these women were satisfied than women with simple mastectomy. Decreased satisfaction with CPM was associated with decreased satisfaction with appearance, complications with reconstruction, reconstruction after CPM, and increased level of stress in life. The majority of women experienced no change or favorable effects in self-esteem (83%), level of stress in life (83%), and emotional stability (88%). Satisfaction with body appearance, feelings of femininity, and sexual relationships were the most adversely affected with 33%, 26%, and 23% of the women responding negatively. Conclusion Although most women are satisfied with CPM, each woman should weigh the benefits alongside the potential adverse effects.
引用
收藏
页码:7849 / 7856
页数:8
相关论文
共 19 条
[1]
Breast Canc Linkage Consortium, 1999, JNCI-J NATL CANCER I, V91, P1310
[2]
FESTINGER L., 1964, CONFLICT DECIS DISSO
[3]
Long-term satisfaction and psychological and social function following bilateral prophylactic mastectomy [J].
Frost, MH ;
Schaid, DJ ;
Sellers, TA ;
Slezak, JM ;
Arnold, PG ;
Woods, JE ;
Petty, PM ;
Johnson, JL ;
Sitta, DL ;
McDonnell, SK ;
Rummans, TA ;
Jenkins, RB ;
Sloan, JA ;
Hartmann, LC .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2000, 284 (03) :319-324
[4]
GIU GP, 2003, PLAST RECONSTR SURG, V111, P125
[5]
The psychological effect of mastectomy with or without breast reconstruction: A prospective, multicenter study [J].
Harcourt, DM ;
Rumsey, NJ ;
Ambler, NR ;
Cawthorn, SJ ;
Reid, CD ;
Maddox, PR ;
Kenealy, JM ;
Rainsbury, RM ;
Umpleby, HC .
PLASTIC AND RECONSTRUCTIVE SURGERY, 2003, 111 (03) :1060-1068
[6]
Impact of medical and demographic factors on long-term quality of life and body image of breast cancer patients [J].
Härtl, K ;
Janni, W ;
Kästner, R ;
Sommer, H ;
Strobl, B ;
Rack, B ;
Stauber, M .
ANNALS OF ONCOLOGY, 2003, 14 (07) :1064-1071
[7]
Prophylactic mastectomy for BRCA1/2 carriers:: Progress and more questions [J].
Hartmann, LC ;
Degnim, A ;
Schaid, DJ .
JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (06) :981-983
[8]
Clinical outcome and patients' satisfaction after simultaneous bilateral breast reconstruction with free transverse rectus abdominis muscle (TRAM) flap [J].
Kovacs, L ;
Papadopulos, NA ;
Ammar, SA ;
Klöppel, M ;
Herschbach, P ;
Heinrich, G ;
Baumann, A ;
Biemer, E .
ANNALS OF PLASTIC SURGERY, 2004, 53 (03) :199-204
[9]
Efficacy of contralateral prophylactic mastectomy in women with a personal and family history of breast cancer [J].
McDonnell, SK ;
Schaid, DJ ;
Myers, JL ;
Grant, CS ;
Donohue, JH ;
Woods, JE ;
Frost, MH ;
Johnson, JL ;
Sitta, DL ;
Slezak, JM ;
Crotty, TB ;
Jenkins, RB ;
Sellers, TA ;
Hartmann, LC .
JOURNAL OF CLINICAL ONCOLOGY, 2001, 19 (19) :3938-3943
[10]
Breast cancer after prophylactic bilateral mastectomy in women with a BRCA1 or BRCA2 mutation. [J].
Meijers-Heijboer, H ;
van Geel, B ;
van Putten, WLJ ;
Henzen-Logmans, SC ;
Seynaeve, C ;
Menke-Pluymers, MBE ;
Bartels, CCM ;
Verhoog, LC ;
van den Ouweland, AMW ;
Niermeijer, MF ;
Brekelmans, CTM ;
Klijn, JGM .
NEW ENGLAND JOURNAL OF MEDICINE, 2001, 345 (03) :159-164