A short synthetic route to the tricyclic guanidinium core of the batzelladine alkaloids

被引：53

作者：

Black, GP

Murphy, PJ ^{[1
]}

Walshe, NDA

机构：

[1] Univ Wales, Dept Chem, Bangor LL57 2UW, Gwynedd, Wales

[2] Pfizer Ltd, Cent Res, Sandwich CT13 9NJ, Kent, England

来源：

TETRAHEDRON | 1998年 / 54卷 / 32期

关键词：

alkaloids; guanidines; Michael reactions;

D O I：

10.1016/S0040-4020(98)00576-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The addition of guanidine to a series of bis-alpha,beta-unsaturated ketones is reported leading to the formation of tricyclic guanidines, which are models of the naturally occurring batzelladine alkaloids. Nmr evidence is given in support of a new assignment for the relative stereochemistry of batzelladine F. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：9481 / 9488

页数：8

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