Bioavailability of nickel in single-wall carbon nanotubes

被引：151

作者：

Liu, Xinyuan

Gurel, Volkan

Morris, Daniel

Murray, David W.

Zhitkovich, Anatoly

Kane, Agnes B.

Hurt, Robert H. ^{[1
]}

机构：

[1] Brown Univ, Div Engn, Providence, RI 02912 USA

[2] Brown Univ, Dept Chem, Providence, RI 02912 USA

[3] Brown Univ, Dept Pathol, Lab Med, Providence, RI 02912 USA

[4] Brown Univ, Dept Geol Sci, Providence, RI 02912 USA

来源：

ADVANCED MATERIALS | 2007年 / 19卷 / 19期

关键词：

D O I：

10.1002/adma.200602696

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The biomolecular mechanism of nickel carcinogenicity is driven by intracellular Ni cation. The role of nickel catalyst in single-wall carbon nanotube toxicity will therefore depend on its bioavailability, which is highly uncertain due to encapsulation by carbon shells. This article measures the material-specific Ni release into extra- and intracellular physiological fluid phases and suggests practical techniques for managing the metals contribution to SWNT toxicity.

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收藏

页码：2790 / +

页数：8

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