Cyclodextrin-assisted capillary electrophoresis for determination of the cyclic nitramine explosives RDX, HMX and CL-20 - Comparison with high-performance liquid chromatography

被引：32

作者：

Groom, CA ^{[1
]}

Halasz, A ^{[1
]}

Paquet, L ^{[1
]}

D'Cruz, P ^{[1
]}

Hawari, J ^{[1
]}

机构：

[1] Natl Res Council Canada, Biotechnol Res Inst, Montreal, PQ H4P 2R2, Canada

来源：

JOURNAL OF CHROMATOGRAPHY A | 2003年 / 999卷 / 1-2期

关键词：

explosives; RDX; HMX; CL-20; nitramines;

D O I：

10.1016/S0021-9673(03)00389-3

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A sulfobutyl ether-beta-cyclodextrin-assisted electrokinetic chromatographic method was developed to rapidly resolve and detect the cyclic nitramine explosives 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaaza-isowurtzitane (CL-20), octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) and hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and their related degradation intermediates in environmental samples. Development of the electrophoretic method required the measurement of the aqueous solubility of CL-20 which was determined to be 3.59 +/- 0.74 mg/l at 25 degreesC (95% confidence interval, n=3). The performance of the method was then compared to results obtained from existing high-performance liquid chromatography methods including US Environmental Protection Agency method 8330. Crown Copyright (C) 2003 Published by Elsevier Science B.V. All rights reserved.

引用

页码：17 / 22

页数：6

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