Dendritic cells and the intestinal bacterial flora: a role for localized mucosal immune responses

被引:74
作者
Uhlig, HH [1 ]
Powrie, F [1 ]
机构
[1] Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England
关键词
D O I
10.1172/JC1200319545
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Mammals coexist in an overall symbiotic relationship with a complex array of commensal bacterial flora that colonizes the gastrointestinal tract. These intestinal bacteria interface with cells of the mucosal immune system, including DCs (see the related article beginning on page 693). Here we discuss mechanisms of interaction between intestinal bacteria and DCs and the role of localized gastrointestinal immune responses.
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收藏
页码:648 / 651
页数:4
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