Pentafluorophenyl 4-nitrobenzenesulfonate as a peptide coupling reagent

被引：6

作者：

Pudhom, K ^{[1
]}

Vilaivan, T ^{[1
]}

机构：

[1] Chulalongkorn Univ, Fac Sci, Dept Chem, Organ Synth Res Unit, Bangkok 10330, Thailand

来源：

SYNTHETIC COMMUNICATIONS | 2001年 / 31卷 / 01期

关键词：

D O I：

10.1081/SCC-100000180

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Protected dipeptides were obtained in good yield by coupling Boc- or Fmoc-protected amino acids with amino acid esters in the presence of pentafluorophenyl 4-nitrobenzenesulfonate (PFNB) as peptide coupling agent and 1-hydroxybenzotriazole as catalyst.

引用

页码：61 / 70

页数：10

共 16 条

[1]

Atherton E., 1989, SOLID PHASE PEPTIDE

[2]

Bodanszky M., 1993, PEPTIDE CHEM PRACTIC

[3] A LOW-EPIMERIZING PEPTIDE COUPLING REAGENT BASED ON THE REARRANGEMENT OF A CARBOXYLIC-SULFONIC MIXED ANHYDRIDE [J].

CABARET, D ;

WAKSELMAN, M .

TETRAHEDRON LETTERS, 1994, 35 (51) :9561-9564

[4] 6-NITRO-1-BETA-NAPHTHALENESULFONYLOXYBENZOTRIAZOLE - A NOVEL COUPLING REAGENT FOR PEPTIDE-SYNTHESIS [J].

DEVADAS, B ;

KUNDU, B ;

SRIVASTAVA, A ;

MATHUR, KB .

TETRAHEDRON LETTERS, 1993, 34 (40) :6455-6458

[5] SOLID-PHASE PEPTIDE-SYNTHESIS UTILIZING 9-FLUORENYLMETHOXYCARBONYL AMINO-ACIDS [J].

FIELDS, GB ;

NOBLE, RL .

INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH, 1990, 35 (03) :161-214

[6] STUDIES ON SYNTHESIS OF HISTIDINE PEPTIDES .1. NIM-TOSYLHISTIDINE DERIVATIVES AS STARTING MATERIALS [J].

FUJII, T ;

SAKAKIBARA, S .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1974, 47 (12) :3146-3151

[7]

FURUKAWA M, 1983, SYNTHESIS-STUTTGART, P42

[8]

ITOH M, 1975, SYNTHESIS-STUTTGART, P456

[9] PEPTIDES .7. SOME SULFONATES OF STRONGLY ACIDIC N-HYDROXY COMPOUNDS AS NOVEL COUPLING REAGENTS [J].

ITOH, M ;

NOJIMA, H ;

NOTANI, J ;

HAGIWARA, D ;

TAKAI, K .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1978, 51 (11) :3320-3329

[10]

ITOH M, 1974, TETRAHEDRON LETT, P3089

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