Long-term follow-up of patients enrolled in a randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer

被引：352

作者：

Roth, JA

Atkinson, EN

Fossella, F

Komaki, R

Ryan, MB

Putnam, JB

Lee, JS

Dhingra, H

De Caro, L

Chasen, M

Hong, WK

机构：

[1] Univ Texas, MD Anderson Canc Ctr, Dept Thorac & Cardiovasc Surg, Houston, TX 77030 USA

[2] Univ Texas, MD Anderson Canc Ctr, Dept Tumor Biol, Houston, TX 77030 USA

[3] Univ Texas, MD Anderson Canc Ctr, Dept Biomath, Houston, TX 77030 USA

[4] Univ Texas, MD Anderson Canc Ctr, Dept Thorac Head & Neck Med Oncol, Houston, TX 77030 USA

[5] Univ Texas, MD Anderson Canc Ctr, Dept Radiotherapy, Houston, TX 77030 USA

[6] Bassett Hlth Care, Dept Surg, Cooperstown, NY 13326 USA

[7] VA Med Ctr, Dept Hematol Oncol, Houston, TX 77030 USA

[8] Baylor Coll Med, Houston, TX 77030 USA

[9] Clin De Genolier, CH-1272 Genolier, Switzerland

[10] Univ Texas, MD Anderson Canc Ctr, Dept Diagnost Radiol, Houston, TX 77030 USA

来源：

LUNG CANCER | 1998年 / 21卷 / 01期

关键词：

lung cancer; induction chemotherapy; randomized trial; cisplatin;

D O I：

10.1016/S0169-5002(98)00046-4

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Our previously reported randomized study of patients with untreated, potentially resectable clinical stage IIIA non-small-cell lung cancer found that patients treated with perioperative chemotherapy and surgery had a significant increase in median survival compared to patients treated with surgery alone. We have now re-analyzed the results of the study with a median time from random allocation to analysis for all patients of 82 months. The increase in survival conferred by perioperative chemotherapy was maintained during the period of extended observation. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：1 / 6

页数：6

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