Chemistry and enzymology of vitamin B12

被引:427
作者
Brown, KL [1 ]
机构
[1] Ohio Univ, Dept Chem & Biochem, Athens, OH 45701 USA
关键词
D O I
10.1021/cr030720z
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The role of ligand substitution in the chemistry and enzymology of vitamin B12 is reviewed. In terms of the chemistry of vitamin B12, its solution chemistry, photochemistry, spectroscopy, protein binding, interaction with nuclei acids, and theoretical aspects are covered. In terms of enzymology, coenzyme B12-dependent enzymes, methyl transferases, and reductive dehalogenases are systematically treated.
引用
收藏
页码:2075 / 2149
页数:75
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