Dimorphism and virulence in Candida albicans

被引:221
作者
Mitchell, AP
机构
[1] Columbia Univ, Dept Microbiol, New York, NY 10032 USA
[2] Columbia Univ, Canc Res Inst, New York, NY 10032 USA
关键词
D O I
10.1016/S1369-5274(98)80116-1
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Two regulatory pathways govern filamentation in the pathogenic fungus Candida albicans. Recent virulence studies of filamentation regulatory mutants argue that both yeast and filamentous forms have roles in infection. Filamentation control pathways seem closely related in C. albicans and in Saccharomyces cerevisiae, thus permitting speculation about C. albicans filamentation genes not yet discovered.
引用
收藏
页码:687 / 692
页数:6
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