Model for nonectatic increase in posterior corneal elevation after ablative procedures

被引:46
作者
Grzybowski, DM
Roberts, CJ
Mahmoud, AM
Chang, JS
机构
[1] Ohio State Univ, Dept Ophthalmol, Columbus, OH 43210 USA
[2] Ohio State Univ, Ctr Biomed Engn, Columbus, OH 43210 USA
[3] Hong Kong Sanat & Hosp, Hong Kong, Hong Kong, Peoples R China
关键词
D O I
10.1016/j.jcrs.2004.10.045
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To evaluate the response of the posterior cornea after uneventful laser in situ keratomileusis (LASIK) with scanning-slit videokeratography using the change in elevation as a measure of biomechanical remodeling. Setting: Hong Kong Sanatorium and Hospital, Hong Kong, China. Methods: Three schematic models of possible posterior corneal response mechanisms to laser refractive surgery were proposed: model A, isolated central bulging; model B, forward shift over a large region of the posterior surface; model C, backward peripheral movement into the anterior chamber. A retrospective study was performed to determine which model was consistent with posterior corneal behavior in 2380 eyes of 1255 patients after myopic LASIK performed with the Technolas 217 laser (Bausch & Lomb). Patients received preoperative and 6-month postoperative Orbscan I (version 2.0, Bausch & Lomb) examinations. Preoperative posterior elevation maps were subtracted from postoperative maps of 2380 eyes using 3 fitting protocols. Difference maps were averaged and the results compared to the proposed schematic models. All topography data processing was done using the Ohio State University Corneal Topography Tool. Results: Significant central increases in posterior elevation corresponded with significant peripheral decreases in posterior elevation. This pattern is consistent with schematic model C, backward peripheral movement of the posterior cornea, possibly due to a differential pattern of swelling. Conclusions: Increases in central posterior corneal elevation after LASIK appear to be dominated by backward peripheral corneal swelling into the anterior chamber rather than forward "bulging" of the central posterior cornea. This is consistent with stable remodeling of the corneal shape due to a surgically induced change in structure and fluid balance, rather than an ectatic event.
引用
收藏
页码:72 / 81
页数:10
相关论文
共 25 条
[1]   Factors affecting the forward shift of posterior corneal surface after laser in situ keratomileusis [J].
Baek, TM ;
Lee, KH ;
Kagaya, F ;
Tomidokoro, A ;
Amano, S ;
Oshika, T .
OPHTHALMOLOGY, 2001, 108 (02) :317-320
[2]  
CASTORO JA, 1988, INVEST OPHTH VIS SCI, V29, P963
[3]  
Dupps WJ, 2001, J REFRACT SURG, V17, P658
[5]   STRUCTURAL THEORY OF SWELLING PRESSURE OF CORNEAL STROMA IN SALINE [J].
HART, RW ;
FARRELL, RA .
BULLETIN OF MATHEMATICAL BIOPHYSICS, 1971, 33 (02) :165-&
[6]   A NEW METHOD FOR THE DETERMINATION OF THE SWELLING PRESSURE OF THE CORNEAL STROMA INVITRO [J].
HEDBYS, BO ;
DOHLMAN, CH .
EXPERIMENTAL EYE RESEARCH, 1963, 2 (02) :122-129
[7]   THE IMBIBITION PRESSURE OF THE CORNEAL STROMA [J].
HEDBYS, BO ;
MISHIMA, S ;
MAURICE, DM .
EXPERIMENTAL EYE RESEARCH, 1963, 2 (02) :99-111
[8]  
Hennighausen H, 1998, INVEST OPHTH VIS SCI, V39, P253
[9]  
HJORTDAL JO, 1995, ACTA OPHTHALMOL SCAN, V73, P12
[10]   Corneal stromal swelling [J].
Hodson, SA .
PROGRESS IN RETINAL AND EYE RESEARCH, 1997, 16 (01) :99-116