Incidence of familial Mediterranean fever (FMF) mutations among children of Mediterranean extraction with functional abdominal pain

被引：13

作者：

Brik, R

Litmanovitz, D

Berkowitz, D

Shamir, R

Rosenthal, E

Shinawi, M

Gershoni-Baruch, R

机构：

[1] Rambam Med Ctr, Dept Pediat, Pediat Gastroenterol & Nutr Unit, IL-31096 Haifa, Israel

[2] Rambam Med Ctr, Inst Human Genet, IL-31096 Haifa, Israel

[3] Technion Israel Inst Technol, Fac Med, Haifa, Israel

来源：

JOURNAL OF PEDIATRICS | 2001年 / 138卷 / 05期

关键词：

D O I：

10.1067/mpd.2001.113357

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Of 59 Sephardic Jewish and Arab children in whom functional abdominal pain was diagnosed, we found that 20% were homozygote for the familial Mediterranean fever gene. Inclusion of genetic screening for familial Mediterranean fever may be advisable in the investigation of recurrent abdominal pain among children of Mediterranean extraction.

引用

页码：759 / 762

页数：4

共 18 条

[1] Mutation and haplotype studies of familial Mediterranean fever reveal new ancestral relationships and evidence for a high carrier frequency with reduced penetrance in the Ashkenazi Jewish population [J].

Aksentijevich, I ;

Torosyan, Y ;

Samuels, J ;

Centola, M ;

Pras, E ;

Chae, JJ ;

Oddoux, C ;

Wood, G ;

Azzaro, MP ;

Palumbo, G ;

Giustolisi, R ;

Pras, M ;

Ostrer, H ;

Kastner, DL .

AMERICAN JOURNAL OF HUMAN GENETICS, 1999, 64 (04) :949-962

[2]

Aksentijevich I, 1997, CELL, V90, P797

[3] RECURRENT ABDOMINAL PAINS - A FIELD SURVEY OF 1,000 SCHOOL CHILDREN [J].

APLEY, J ;

NAISH, N .

ARCHIVES OF DISEASE IN CHILDHOOD, 1958, 33 (168) :165-170

[4]

APLEY J, 1998, LANCET, V351, P659

[5]

Bernot A, 1997, NAT GENET, V17, P25

[6]

BOYLE JT, 1996, PEDIAT GASTROINTESTI, P205

[7] Familial Mediterranean fever: Clinical and genetic characterization in a mixed pediatric population of Jewish and Arab patients [J].

Brik, R ;

Shinawi, M ;

Kepten, I ;

Berant, M ;

Gershoni-Baruch, R .

PEDIATRICS, 1999, 103 (05)

[8] Phenotype-genotype correlation in Jewish patients suffering from familial Mediterranean fever (FMF) [J].

Dewalle, M ;

Domingo, C ;

Rozenbaum, M ;

Ben-Chétrit, E ;

Cattan, D ;

Bernot, A ;

Dross, C ;

Dupont, M ;

Notarnicola, C ;

Levy, M ;

Rosner, I ;

Demaille, J ;

Touitou, I .

EUROPEAN JOURNAL OF HUMAN GENETICS, 1998, 6 (01) :95-97

[9]

Gershoni-Baruch R, 1999, Hum Mutat, V14, P91, DOI 10.1002/(SICI)1098-1004(1999)14:1<91::AID-HUMU22>3.0.CO

[10]

2-8

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