Innate and adaptive immune responses to Listeria monocytogenes:: a short overview

被引：136

作者：

Zenewicz, Lauren A.

Shen, Hao ^{[1
]}

机构：

[1] Univ Penn, Sch Med, Dept Microbiol, Philadelphia, PA 19104 USA

[2] Yale Univ, Sch Med, Dept Immunobiol, New Haven, CT 06520 USA

来源：

MICROBES AND INFECTION | 2007年 / 9卷 / 10期

关键词：

Listeria monocytogenes; immunity; infection;

D O I：

10.1016/j.micinf.2007.05.008

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The Gram-positive facultative intracellular bacterium Listeria monocytogenes is a model pathogen for elucidating important mechanisms of the immune response. Infection of mice with a sub-lethal dose of bacteria generates highly reproducible innate and adaptive immune responses, resulting in clearance of the bacteria and resistance to subsequent L. monocytogenes infection. Both the innate and adaptive immune systems are crucial to the recognition and elimination of this pathogen from the host. (C) 2007 Elsevier Masson SAS. All rights reserved.

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收藏

页码：1208 / 1215

页数：8

相关论文

共 82 条

[1] Immunological memory and protective immunity: Understanding their relation [J].

Ahmed, R ;

Gray, D .

SCIENCE, 1996, 272 (5258) :54-60

[2] Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes [J].

Auerbuch, V ;

Brockstedt, DG ;

Meyer-Morse, N ;

O'Riordan, M ;

Portnoy, DA .

JOURNAL OF EXPERIMENTAL MEDICINE, 2004, 200 (04) :527-533

[3] NATURAL IMMUNITY - A T-CELL-INDEPENDENT PATHWAY OF MACROPHAGE ACTIVATION, DEFINED IN THE SCID MOUSE [J].

BANCROFT, GJ ;

SCHREIBER, RD ;

UNANUE, ER .

IMMUNOLOGICAL REVIEWS, 1991, 124 :5-24

[4]

BERCHE P, 1987, J IMMUNOL, V138, P2266

[5]

Bhardwaj V, 1998, J IMMUNOL, V160, P376

[6] Neutrophil extracellular traps kill bacteria [J].

Brinkmann, V ;

Reichard, U ;

Goosmann, C ;

Fauler, B ;

Uhlemann, Y ;

Weiss, DS ;

Weinrauch, Y ;

Zychlinsky, A .

SCIENCE, 2004, 303 (5663) :1532-1535

[7] Cytoplasmic entry of Listeria monocytogenes enhances dendritic cell maturation and T cell differentiation and function [J].

Brzoza, KL ;

Rockel, AB ;

Hiltbold, EM .

JOURNAL OF IMMUNOLOGY, 2004, 173 (04) :2641-2651

[8] Coordinate regulation of complex T cell populations responding to bacterial infection [J].

Busch, DH ;

Pilip, IM ;

Vijh, S ;

Pamer, EG .

IMMUNITY, 1998, 8 (03) :353-362

[9] Lymphocytes are detrimental during the early innate immune response against Listeria monocytogenes [J].

Carrero, JA ;

Calderon, B ;

Unanue, ER .

JOURNAL OF EXPERIMENTAL MEDICINE, 2006, 203 (04) :933-940

[10] Type I interferon sensitizes lymphocytes to apoptosis and reduces resistance to listeria infection [J].

Carrero, JA ;

Calderon, B ;

Unanue, ER .

JOURNAL OF EXPERIMENTAL MEDICINE, 2004, 200 (04) :535-540

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