COX-2 as a multifunctional neuronal modulator

被引：100

作者：

Bazan, NG ^{[1
]}

机构：

[1] Louisiana State Univ, Hlth Sci Ctr, Sch Med, Ctr Neurosci, New Orleans, LA 70119 USA

[2] Louisiana State Univ, Hlth Sci Ctr, Sch Med, Dept Ophthalmol, New Orleans, LA USA

来源：

NATURE MEDICINE | 2001年 / 7卷 / 04期

关键词：

D O I：

10.1038/86477

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

COX-2 is involved in prostaglandin synthesis and expressed throughout the nervous system, where it participates in pain sensitivity and in synaptic plasticity. Microsomal prostaglandin E synthase, expressed throughout the nervous system microvasculature, may be another important player in neural aspects of the inflammatory response.

引用

页码：414 / 415

页数：2

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