Chemoselective tetrahydropyranylation of alcohols and phenols using polystyrene supported aluminium chloride as a catalyst

被引：64

作者：

Tamami, B ^{[1
]}

Borujeny, KP ^{[1
]}

机构：

[1] Shiraz Univ, Dept Chem, Shiraz 71454, Iran

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 04期

关键词：

protection; terahydropyranylation; aluminium chloride; polymer supported Lewis acid;

D O I：

10.1016/j.tetlet.2003.11.056

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple, efficient and highly chemoselective method for tetrahydropyranylation of alcohols and phenols has been developed by their reaction with 3,4-dihydro-2H-pyran at room temperature in the presence of a catalytic amount of polystyrene supported AlCl3. The method is also highly selective for monoprotection of symmetrical diols. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：715 / 718

页数：4

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[2]

ALPER H, 1972, SYNTH-INT J METHODS, P81

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