Aerosol treatment of cystic fibrosis

被引：25

作者：

Garcia-Contreras, L ^{[1
]}

Hickey, AJ ^{[1
]}

机构：

[1] Univ N Carolina, Div Drug Delivery & Disposit, Sch Pharm, Chapel Hill, NC 27599 USA

来源：

CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS | 2003年 / 20卷 / 05期

关键词：

aerosol therapy; pulmonary deposition; particle size; antibiotics; bronchodilators; gene therapy;

D O I：

10.1615/CritRevTherDrugCarrierSyst.v20.i5.10

中图分类号：

R9 [药学];

学科分类号：

1007 [药学];

摘要：

Different aerosol therapies have been employed to treat the underlying cause and symptoms of cystic fibrosis (CF) during the past two decades. A summary of the main elements of the disease and aerosol treatments employed in clinical care and experimental trials are presented. Methods of aerosol generation and characterization are reviewed. Suggestions for improving the current treatments are provided.

引用

页码：317 / 356

页数：40

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