A novel and facile carbodiimide-mediated synthesis of 2,3-dihydro-6H-pyrimido[2,1-b]quinazolin-4(1H)-ones via a tandem intramolecular nucleophilic addition intramolecular hetero conjugate addition annulation strategy

被引：21

作者：

Saito, T

Tsuda, K

机构：

[1] Department of Chemistry, Faculty of Science, Science University of Tokyo, Tokyo 162, Kagurazaka, Shinjuku-ku

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 50期

关键词：

D O I：

10.1016/S0040-4039(96)02131-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel and efficient carbodiimide-mediated synthetic method for new 2,3-dihydro-6H-pyrimido[2,1-b]quinazolin-4(1H)-ones (1) is described which involves initial intramolecular addition of an amino-nucleophile to the carbodiimide-cumulenic system, followed by intramolecular hetero conjugate addition annulation. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：9071 / 9072

页数：2

共 21 条

[1]

[Anonymous], RUSS CHEM REV

[2] SYNTHESIS OF REACTIVITY OF LAMBDA-5-PHOSPHAZENES - USES AS SYNTHETIC INTERMEDIATES [J].