Toxic effects of chromatographic fractions of Phyllanthus amarus on the serum biochemistry of rats

被引：12

作者：

Adedapo, AA ^{[1
]}

Abatan, MO

Idowu, SO

Olorunsogo, OO

机构：

[1] Univ Ibadan, Dept Vet Physiol Pharmacol, Ibadan, Nigeria

[2] Univ Ibadan, Dept Pharmaceut Chem, Ibadan, Nigeria

[3] Univ Ibadan, Dept Biochem, Ibadan, Nigeria

来源：

PHYTOTHERAPY RESEARCH | 2005年 / 19卷 / 09期

关键词：

Phyllanthus amarus; chromatography; serum biochemistry; toxicity;

D O I：

10.1002/ptr.1721

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Chromatographic fractions obtained from Phyllanthus amarus were tested for toxicity on the serum biochemistry of rats. The results revealed that some fractions of P. amarus had potentially deleterious effects on the blood and therefore caution should be exercised in the use of P. amarus as a medicinal plant. Copyright (c) 2005 John Wiley & Sons, Ltd.

引用

页码：812 / 815

页数：4

共 15 条

[1]

BLUMBERG BS, 1989, CANCER DETECT PREV, V14, P195

[2]

CARROLL EJ, 1965, J AM VET MED ASSOC, V46, P1300

[3]

DUNCAN JR, 1994, VET LAB MED CLIN PAT, P21

[4]

Harborne JB, 1984, PHYTOCHEMICAL METHOD, V2nd, P9

[5]

HOFFMANN WE, 1977, AM J VET RES, V38, P1637

[6] HIV-1 REVERSE-TRANSCRIPTASE INHIBITOR FROM PHYLLANTHUS-NIRURI [J].

OGATA, T ;

HIGUCHI, H ;

MOCHIDA, S ;

MATSUMOTO, H ;

KATO, A ;

ENDO, T ;

KAJI, A ;

KAJI, H .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 1992, 8 (11) :1937-1944

[7]

SAINI PK, 1978, AM J VET RES, V39, P1510

[8] A REVIEW OF THE TOXICITY OF LANTANA-CAMARA (LINN) IN ANIMALS [J].

SHARMA, OP ;

MAKKAR, HPS ;

DAWRA, RK ;

NEGI, SS .

CLINICAL TOXICOLOGY, 1981, 18 (09) :1077-1094

[9] EFFECTS OF PHYLLANTHUS PLANT-EXTRACTS ON DUCK HEPATITIS-B VIRUS INVITRO AND INVIVO [J].

SHEAD, A ;

VICKERY, K ;

PAJKOS, A ;

MEDHURST, R ;

FREIMAN, J ;

DIXON, R ;

COSSART, Y .

ANTIVIRAL RESEARCH, 1992, 18 (02) :127-138

[10]

STEEL RGD, 1986, PRINCIPLES PROCEDURE, P6

← 1 2 →