A new pentacyclic triterpenoid glucoside from Prunus serrulata var. spontanea

被引：32

作者：

Jung, HA

Chung, HY

Jung, JH

Choi, JS ^{[1
]}

机构：

[1] Pukyong Natl Univ, Fac Food Sci & Biotechnol, Pusan 608737, South Korea

[2] Pusan Natl Univ, Coll Pharm, Pusan 609735, South Korea

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2004年 / 52卷 / 01期

关键词：

Prunus serrulata var. spontanea; Rosaceae; triterpenoids; 2; alpha; 3; 24-trihydroxyurs-12-en-28-oic acid-28-O-beta-D-glucopyranosyl ester; ONOO-; scavenging activity;

D O I：

10.1248/cpb.52.157

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

A new triterpenoid, 2alpha,3alpha,24-trihydroxyurs-12-en-28-oic acid-28-O-beta-D-glucopyranosyl ester (4) along with four known triterpenoids, ursolic acid (1), 2alpha-hydroxyursolic acid (2), 2alpha,3alpha,24-trihydroxyurs-12-en-28-oic acid (3), and 2alpha,3alpha,19alpha;24-tetrahydroxyurs-12-en-28-oic acid-28-O-beta-D-glucopyranosyl ester (5), were isolated from the leaves of Prunus serrulata var. spontanea (Rosaceae). Compounds 3-5 showed ONOO- scavenging activity, whereas compounds 1 and 2 were virtually inactive.

引用

页码：157 / 159

页数：3

共 13 条

[1]

CHUSHENG H, 1998, ACTA BOT YUNNANICA, V10, P93

[2]

Triterpene phytoalexins from nectarine fruits [J].