Analysis of tetrodotoxin

被引：32

作者：

Alcaraz, A ^{[1
]}

Whipple, RE ^{[1
]}

Gregg, HR ^{[1
]}

Andresen, BD ^{[1
]}

Grant, PM ^{[1
]}

机构：

[1] Univ Calif Lawrence Livermore Natl Lab, Forens Sci Ctr, Livermore, CA 94550 USA

来源：

FORENSIC SCIENCE INTERNATIONAL | 1999年 / 99卷 / 01期

关键词：

tetrodotoxin; electrospray-ionization mass spectrometry;

D O I：

10.1016/S0379-0738(98)00171-6

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

Law enforcement personnel interdicted an illegal shipment of a chemical suspected to be an illicit drug. However, literature within the package indicated that the substance was actually tetrodotoxin, a potent marine neurotoxin. Analyses of the questioned samples by gas chromatography-mass spectrometry revealed no evidence for the presence of illicit drugs, but this technique was ineffectual for the identification of tetrodotoxin. Direct-inlet-probe mass spectrometry was likewise unable to characterize the chemical identity of the subject material. Electrospray-ionization mass spectrometry was implemented to successfully identify the interdicted substance as tetrodotoxin. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：35 / 45

页数：11

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