A highly active catalyst system for the heteroarylation of acetone

被引：20

作者：

Liu, P ^{[1
]}

Lanza, TJ ^{[1
]}

Jewell, JP ^{[1
]}

Jones, CP ^{[1
]}

Hagmann, WK ^{[1
]}

Lin, LS ^{[1
]}

机构：

[1] Merck & Co Inc, Merck Res Labs, Dept Med Chem, Rahway, NJ 07065 USA

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 49期

关键词：

D O I：

10.1016/j.tetlet.2003.09.176

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly active catalyst system for the heteroarylation of acetone has been identified. The Coupling between the in situ generated tributyltin enolate of acetone and a variety of heteroaromatic bromides, chlorides, and triflates in the presence of this catalyst system provided arylacetones in good yields. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：8869 / 8871

页数：3

共 13 条

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