Analysis of virus-specific CD4+ T cells during long-term gammaherpesvirus infection

被引：40

作者：

Flaño, E

Woodland, DL

Blackman, MA

Doherty, PC

机构：

[1] St Jude Childrens Res Hosp, Dept Immunol, Memphis, TN 38105 USA

[2] Trudeau Inst Inc, Saranac Lake, NY 12983 USA

来源：

JOURNAL OF VIROLOGY | 2001年 / 75卷 / 16期

关键词：

D O I：

10.1128/JVI.75.16.7744-7748.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Major histocompatibility complex class II-mediated antigen presentation after intranasal infection with murine gammaherpesvirus 68 differs in mediastinal lymph nodes and spleen. Evidence that virus-specific CD4(+) T cells were being stimulated was found as late as 6 to 8 months after infection, and cells specific for the viral gp150(67-83) and ORF11(168-180) peptides were maintained as a fairly stable proportion of the total response.

引用

收藏

页码：7744 / 7748

页数：5

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