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Cell transplantation as a treatment for retinal disease

被引：103
作者：
Lund, RD
Kwan, ASL
Keegan, DJ
Sauvé, Y
Coffey, PJ
Lawrence, JM
机构：
[1] Inst Ophthalmol, London EC1V 9EL, England
[2] Univ Sheffield, Dept Psychol, Sheffield S10 2TP, S Yorkshire, England
来源：
PROGRESS IN RETINAL AND EYE RESEARCH | 2001年 / 20卷 / 04期
基金：
英国惠康基金; 英国医学研究理事会;
关键词：
D O I：
10.1016/S1350-9462(01)00003-9
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
It has been shown that photoreceptor degeneration can be limited in experimental animals by transplantation of fresh RPE to the subretinal space. There is also evidence that retinal cell transplants can be used to reconstruct retinal circuitry in dystrophic animals. Here we describe and review recent developments that highlight the necessary steps that should be taken prior to embarking on clinical trials in humans. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：415 / 449
页数：35
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