InAs/InP/ZnSe Core/Shell/Shell Quantum Dots as Near-Infrared Emitters: Bright, Narrow-Band, Non-Cadmium Containing, and Biocompatible

被引：98

作者：

Xie, Renguo ^{[1
]}

Chen, Kai ^{[2
,3
]}

Chen, Xiaoyuan ^{[2
,3
]}

Peng, Xiaogang ^{[1
]}

机构：

[1] Univ Arkansas, Dept Chem & Biochem, Fayetteville, AR 72701 USA

[2] Stanford Univ, Sch Med, Dept Radiol, MIPS, Stanford, CA 94305 USA

[3] Stanford Univ, Sch Med, Bio X Program, Stanford, CA 94305 USA

来源：

NANO RESEARCH | 2008年 / 1卷 / 06期

基金：

美国国家科学基金会;

关键词：

Quantum dots; InAs; near-infrared (NIR); toxicity;

D O I：

10.1007/s12274-008-8048-x

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

High quality InAs/InP/ZnSe core/shell/shell quantum dots have been grown by a one-pot approach. This engineered quantum dots with unique near-infrared (NIR) fluorescence, possessing outstanding optical properties, and the biocompatibility desired for in vivo applications. The resulting quantum dots have significantly lower intrinsic toxicity compared to NIR emissive dots containing elements such as cadmium, mercury, or lead. Also, these newly developed ultrasmall non-Cd containing and NIR-emitting quantum dots showed significantly improved circulation half-life and minimal reticuloendothelial system (RES) uptake.

引用

页码：457 / 464

页数：8

共 21 条

[1] Synthesis of InAs/CdSe/ZnSe core/shell1/shell2 structures with bright and stable near-infrared fluorescence [J].

Aharoni, A ;

Mokari, T ;

Popov, I ;

Banin, U .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (01) :257-264

[2] Formation of high quality InP and InAs nanocrystals in a noncoordinating solvent [J].

Battaglia, D ;

Peng, XG .

NANO LETTERS, 2002, 2 (09) :1027-1030

[3] Semiconductor nanocrystals as fluorescent biological labels [J].

Bruchez, M ;

Moronne, M ;

Gin, P ;

Weiss, S ;

Alivisatos, AP .

SCIENCE, 1998, 281 (5385) :2013-2016

[4] Peptide-labeled near-infrared quantum dots for imaging tumor vasculature in living subjects [J].

Cai, WB ;

Shin, DW ;

Chen, K ;

Gheysens, O ;

Cao, QZ ;

Wang, SX ;

Gambhir, SS ;

Chen, XY .

NANO LETTERS, 2006, 6 (04) :669-676

[5]

Cao YW, 1999, ANGEW CHEM INT EDIT, V38, P3692, DOI 10.1002/(SICI)1521-3773(19991216)38:24<3692::AID-ANIE3692>3.0.CO

[6]

2-W

[7] Quantum dot bioconjugates for ultrasensitive nonisotopic detection [J].

Chan, WCW ;

Nie, SM .

SCIENCE, 1998, 281 (5385) :2016-2018

[8] In vivo imaging of quantum dots encapsulated in phospholipid micelles [J].

Dubertret, B ;

Skourides, P ;

Norris, DJ ;

Noireaux, V ;

Brivanlou, AH ;

Libchaber, A .

SCIENCE, 2002, 298 (5599) :1759-1762

[9] In vivo cancer targeting and imaging with semiconductor quantum dots [J].

Gao, XH ;

Cui, YY ;

Levenson, RM ;

Chung, LWK ;

Nie, SM .

NATURE BIOTECHNOLOGY, 2004, 22 (08) :969-976

[10] Colloidal chemical synthesis and characterization of InAs nanocrystal quantum dots [J].

Guzelian, AA ;

Banin, U ;

Kadavanich, AV ;

Peng, X ;

Alivisatos, AP .

APPLIED PHYSICS LETTERS, 1996, 69 (10) :1432-1434

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