Toxicity of binary mixtures of organic chemicals to microorganisms

被引：43

作者：

Prakash, J ^{[1
]}

Nirmalakhandan, N ^{[1
]}

Sun, B ^{[1
]}

Peace, J ^{[1
]}

机构：

[1] NEW MEXICO STATE UNIV,CIVIL AGR & GEOL ENGN DEPT,LAS CRUCES,NM 88003

来源：

WATER RESEARCH | 1996年 / 30卷 / 06期

关键词：

joint toxicity; binary mixture toxicity; Polytox; QSAR models;

D O I：

10.1016/0043-1354(95)00246-4

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Inhibition of microorganisms by single and binary mixtures of organic chemicals was experimentally determined using the respirometric technique. Single chemical dose-response relationships in these assays most closely fit the Probit versus the Weibit and Legit transformations. A QSAR-based approach was developed to predict the joint effects in the binary mixtures. The validity of the proposed approach was demonstrated by comparing the predicted values against the experimentally determined values. Good agreement between the two was found with a coefficient of determination, r(2) = 0.892. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：1459 / 1463

页数：5

共 9 条

[1]

BEIESINGER KE, 1986, EXOTOX ENV SAFETY, V11, P9

[2]

BLUM DJW, 1989, THESIS DREXEL U PHIL

[3]

CHRISTENSEN ER, 1989, HAZARD ASSESSMENT CH, V6

[4] MEASUREMENT OF POTENCIES OF DRUG MIXTURES [J].

HEWLETT, PS .

BIOMETRICS, 1969, 25 (03) :477-&

[5] TOXICITY OF MIXTURES OF ORGANIC-CHEMICALS TO MICROORGANISMS [J].

NIRMALAKHANDAN, N ;

ARULGNANENDRAN, V ;

MOHSIN, M ;

SUN, B ;

CADENA, F .

WATER RESEARCH, 1994, 28 (03) :543-551

[6]

PLACKETT RL, 1952, J ROY STAT SOC B, V14, P141

[7] ESTIMATING TOXICITY OF ORGANIC-CHEMICALS TO ACTIVATED-SLUDGE MICROORGANISMS [J].

SUN, B ;

NIRMALAKHANDAN, N ;

HALL, E ;

WANG, XH ;

PRAKASH, J ;

MAYNES, R .

JOURNAL OF ENVIRONMENTAL ENGINEERING-ASCE, 1994, 120 (06) :1459-1469

[8] QSAR PARAMETERS FOR TOXICITY OF ORGANIC-CHEMICALS TO NITROBACTER [J].

TANG, NH ;

BLUM, DJW ;

NIRMALAKHANDAN, N ;

SPEECE, RE .

JOURNAL OF ENVIRONMENTAL ENGINEERING-ASCE, 1992, 118 (01) :17-37

[9] TOXICITY OF A MIXTURE OF METALS ON FRESHWATER ALGAE [J].

WONG, PTS ;

CHAU, YK ;

LUXON, PL .

JOURNAL OF THE FISHERIES RESEARCH BOARD OF CANADA, 1978, 35 (04) :479-481

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