Site-selective DNA binding drugs

被引：10

作者：

Ebbinghaus, SW ^{[1
]}

机构：

[1] Univ Arizona, Arizona Canc Ctr, Tucson, AZ 85724 USA

来源：

CHEMISTRY & BIOLOGY | 2003年 / 10卷 / 10期

关键词：

D O I：

10.1016/j.chembiol.2003.10.004

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Last month in Chemistry & Biology, Gottesfeld and colleagues demonstrated that designer DNA binding drugs could inhibit the expression of target genes in cultured human cells. This landmark observation provides proof-of-concept for the artificial control of gene expression in living cells.

引用

页码：895 / 897

页数：3

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