Long-term results of in situ split-liver transplantation

Background. Split-liver transplantation (SLT) offers immediate expansion of the cadaver donor pool. The principal beneficiaries have been adult and pediatric recipients with excellent outcomes. This study analyzed a single-center experience of adult to adult in situ SLT in adult recipients. Patients and methods. Fourteen consecutive adult-to-adult in situ SLT have been performed at our institution since 1998. The extended right lobe comprising segment I was transplanted in to adult patients, the left lateral segment, for pediatric transplants. Results. Donors of SLT were significantly younger (P =.03) than those of whole liver transplants. Survival rates of patients receiving a split liver were 83%, 73%, and 73% at 1, 3, and 5 years after the transplant respectively and grafts of 73%, 73%, and 73% for SLT and 76%, 70%, and 66% for whole liver transplants (P =.44). The rate of biliary complication after SLT was 21%, which was comparable to that after whole organ transplantation (17%). The incidence of hepatic artery thrombosis and primary nonfunction was not significantly different between split liver and whole organ transplantation performed during the same time period (7% versus 4.6% P =.67 and 7% versus 2.6% P =.32, respectively). Conclusion. This limited single-center experience confirmed that both early and longterm results of SLT are comparable to those of traditional whole liver organ transplantation.