One-step synthesis of the vicinal dinitroguaianolides achillin and grossmisin

被引：3

作者：

Alebastrov, OV

Raldugin, VA

Bagryanskaya, IY

Gatilov, YV

Shakirov, MM

Kulyyasov, AT

Adekenov, SM

机构：

[1] Russian Acad Sci, NN Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Div, Novosibirsk 630090, Russia

[2] Inst Phytochem, Minist Educ & Sci, Karaganda 470032, Kazakhstan

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2003年 / 39卷 / 04期

关键词：

sesquiterpenoids; guaianolides; grossmisin; achillin; nitrosochlorination; nitro compounds;

D O I：

10.1023/B:CONC.0000003417.79920.8d

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

1,10-Dihydro-1alpha,10alpha-dinitrogrossmisin was synthesized by bubbling gaseous nitrosyl chloride through a chloroform solution of the guaianolide grossmisin. The molecular structure was determined by X-ray. It was found that the formation of similar dinitrates is accelerated by using NOCl containing nitrogen dioxide.

引用

页码：362 / 365

页数：4