Phenylpropanoid glycosides from Orobanche caerulescens

被引：30

作者：

Lin, LC ^{[1
]}

Chiou, WF ^{[1
]}

Chou, CJ ^{[1
]}

机构：

[1] Natl Res Inst Chinese Med, Taipei 112, Taiwan

来源：

PLANTA MEDICA | 2004年 / 70卷 / 01期

关键词：

Orobanchaceae; Orobanche caerulescens; phenylpropanoid glycosides; caerulescenoside; 3 '-methyl crenatoside; antioxidant;

D O I：

10.1055/s-2004-815455

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new phenylpropanoid glycosides, caerulescenoside (1), and 3'-methyl crenatoside (2), as well as five known phenylpropanoid glycosides [acteoside (3), isoacteoside (4), campneoside 11 (5), crenatoside (6), and desrhamnosyl acteoside (7)] were isolated from the whole plant of Orobanche caerulescens. The antioxidative effects of compounds I - 7 on human low-density lipoprotein were evaluated. All these compounds suppress concentration-dependently conjugated diene formation with IC50 values of 1.25 +/- 0.06, 2.97 +/- 0.31, 0.31 +/- 0.01, 1.01 +/- 0.05, 1.15 +/- 0.04, 1.69 +/- 0.15, and 0.64 +/- 0.03 muM respectively. Comparison of their antioxidative activities with that of resveratrol (IC50: 6.75 +/- 1.05 MM), a natural phenolic antioxidant isolated from grape, demonstrated that the prolonged effect on lag-time and the damping effect on oxidative rate by compounds I - 7 were all more potent.

引用

页码：50 / 53

页数：4

共 14 条

[1] CRENATOSIDE - A NOVEL PHENYLPROPANOID GLYCOSIDE FROM OROBANCHE-CRENATA [J].