Hormones in the critically ill patient: to intervene or not to intervene?

被引:25
作者
Ligtenberg, JJM
Girbes, ARJ
Beentjes, JAM
Tulleken, JE
van der Werf, TS
Zijlstra, JG
机构
[1] Univ Groningen Hosp, Dept Internal Med, Intens & Resp Care Unit ICB, NL-9700 RB Groningen, Netherlands
[2] Ny Smellinghe Hosp, Dept Internal Med, Drachten, Netherlands
[3] Free Univ Amsterdam Hosp, Surg Intens Care Unit, Amsterdam, Netherlands
关键词
critical illness; thyroid hormones; growth hormone; prolactin; cortisol; synacthen; relative adrenal insufficiency syndrome; insulin resistance; norepinephrine; intensive care;
D O I
10.1007/s001340101050
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Critically ill patients show a variety of hormonal changes that appear to differ considerably in acute and prolonged critical illness. Whether these endocrine alterations serve as physiological adaptation or contribute to further deterioration remains an intriguing question. We review the recent literature and discuss whether measuring circulating hormone concentrations, performing stimulation tests, and intervening with hormone substitution could contribute to the recovery of critically ill patients.
引用
收藏
页码:1567 / 1577
页数:11
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