Helicobacter pylori primary resistant strains over 11 years in French children

被引：45

作者：

Kalach, Nicolas

Serhal, Lydia

Asmar, Edgar

Campeotto, Florence

Bergeret, Michel

Dehecq, Eric

Spyckerelle, Claire

Charkaluk, Marie-Laure

Decoster, Anne

Dupont, Christophe

Raymond, Josette ^{[1
]}

机构：

[1] Univ Paris V Hop Cochin St Vincent Paul, Serv Bacteriol, F-75679 Paris 14, France

[2] Univ Catholique, Hop St Philibert, Serv Bacteriol, F-59462 Lomme Les Lille, France

[3] Univ Catholique Lille, Hop St Vincent de Paul, Clin Pediatrie St Antoine, F-59020 Lille, France

[4] Univ Paris V Hop Cochin St Vincent Paul, Dept Neonatol Pediatrie, F-75674 Paris 14, France

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2007年 / 59卷 / 02期

关键词：

Helicobacter pylori; antimicrobial resistance; clarithromycin; metronidazole; children;

D O I：

10.1016/j.diagmicrobio.2007.05.003

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The yearly prevalence between 1994 and 2005 of primary resistance to amoxicillin, metronidazole, and clarithromycin of 377 Helicobacter pylori strains isolated from children was studied, All the H. pylori strains were susceptible to amoxicillin, 138/377 (36.7%) were resistant to metronidazole, 86/377 (22.8%) to clarithromycin, and 30/377 (7.9%) to both metronidazole and clarithromycin. Over the entire period, resistance to clarithromycin did not change, whereas metronidazole resistance decreased significantly from 43.3% (1994-1998) to 32% (1999-2005), P = 0.001. (C) 2007 Elsevier Inc. All rights reserved.

引用

页码：217 / 222

页数：6

共 41 条

[1] Clarithromycin resistance among Helicobacter pylori strains isolated from children:: Prevalence and study of mechanism of resistance by PCR-restriction fragment length polymorphism analysis [J].