Do CD8+CD25+cells predict immune reconstitution syndrome in HIV-positive patients who begin HAART?

被引:8
作者
Cianchetta-Sivori, Malena [1 ]
Raso, Sandra
Fernandez-Guerrero, Manuel
Gorgolas, Miguel
Garcia, Rosa
机构
[1] Fdn Jimenez Diaz Capio, Dept Immunol, Madrid, Spain
[2] Fdn Jimenez Diaz Capio, Dept Infect Dis, Madrid, Spain
关键词
D O I
10.1097/QAD.0b013e3282f125da
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Although undesirable, immune reconstitution syndrome (IRS) indicates a favourable effect of HAART and it should be differentiated from an opportunistic infection because of their distinct implications and management. Our group analysed different immunological parameters with the aim of identifying IRS predictors in patients who begin HAART. We found that CD8(+)CD25(+) cell pretreatment values in patients who developed IRS were four times higher than in those patients who did not develop IRS.
引用
收藏
页码:2347 / 2349
页数:3
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