Transesterification of trialkyl phosphates from alkyl bromides

被引：6

作者：

Lherbet, C ^{[1
]}

Castonguay, R ^{[1
]}

Keillor, JW ^{[1
]}

机构：

[1] Univ Montreal, Dept Chem, Montreal, PQ H3C 3J7, Canada

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 20期

基金：

加拿大自然科学与工程研究理事会;

关键词：

phosphate triester; transesterification; bromide;

D O I：

10.1016/j.tetlet.2005.03.065

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The treatment of trialkyl phosphate with different alkyl bromides provides facile access to mixed phosphate esters. The presence of substoichiometric amounts of lithium bromide was found to be critical to this transesterification process, supporting a mechanism involving initial generation of phosphate anion, followed by its nucleophilic attack on alkyl bromide. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：3565 / 3567

页数：3

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