Antioxidant flavonoid glycosides from Daphniphyllum calycinum

被引:99
作者
Gamez, EJC
Luyengi, L
Lee, SK
Zhu, LF
Zhou, BN
Fong, HHS
Pezzuto, JM
Kinghorn, AD [1 ]
机构
[1] Univ Illinois, Coll Pharm, Program Collaborat Res Pharmaceut Sci, Chicago, IL 60612 USA
[2] Univ Illinois, Coll Pharm, Dept Med Chem & Pharmacognosy, Chicago, IL 60612 USA
[3] Acad Sinica, S China Inst Bot, Guangzhou, Peoples R China
[4] Acad Sinica, Shanghai Inst Mat Med, Shanghai, Peoples R China
来源
JOURNAL OF NATURAL PRODUCTS | 1998年 / 61卷 / 05期
关键词
D O I
10.1021/np9800203
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
A novel flavonoid diglycoside, 5,6,7,4'-tetrahydroxyflavonol 3-O-rutinoside (1), and a previously known compound, kaempferol 3-O-neohesperidoside (2), were isolated from an ethyl acetate extract of Daphniphyllum calycinum leaves that showed significant activity in a 1,1-diphenyl-2-picrylhydrazyl (DPPH) free-radical assay. The structure of 1 was elucidated by a combination of spectroscopic methods, and compounds 1 and 2 were found to be moderately active as antioxidants in the DPPH assay.
引用
收藏
页码:706 / 708
页数:3
相关论文
共 11 条
  • [1] Agrawal P. K., 1989, CARBON 13 NMR FLAVON, P95
  • [2] NMR-SPECTROSCOPY IN THE STRUCTURAL ELUCIDATION OF OLIGOSACCHARIDES AND GLYCOSIDES
    AGRAWAL, PK
    [J]. PHYTOCHEMISTRY, 1992, 31 (10) : 3307 - 3330
  • [3] ARTHUR H. R., 1965, PHYTOCHEMISTRY, V4, P627, DOI 10.1016/S0031-9422(00)86225-1
  • [4] The flavonoids of Allium ursinum
    Carotenuto, A
    DeFeo, V
    Fattorusso, E
    Lanzotti, V
    Magno, S
    Cicala, C
    [J]. PHYTOCHEMISTRY, 1996, 41 (02) : 531 - 536
  • [5] Antioxidant properties of hydroxy-flavones
    Cotelle, N
    Bernier, JL
    Catteau, JP
    Pommery, J
    Wallet, JC
    Gaydou, EM
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 1996, 20 (01) : 35 - 43
  • [6] 8-METHOXYKAEMPFEROL 3-NEOHESPERIDOSIDE AND OTHER FLAVONOIDS FROM BEE POLLEN OF CRATAEGUS-MONOGYNA
    DAUGUET, JC
    BERT, M
    DOLLEY, J
    BEKAERT, A
    LEWIN, G
    [J]. PHYTOCHEMISTRY, 1993, 33 (06) : 1503 - 1505
  • [7] GRAY DE, 1971, ASIAN J MED, V7, P409
  • [8] C-13 NMR-STUDIES OF FLAVONOIDS .3. NATURALLY OCCURRING FLAVONOID GLYCOSIDES AND THEIR ACYLATED DERIVATIVES
    MARKHAM, KR
    TERNAI, B
    STANLEY, R
    GEIGER, H
    MABRY, TJ
    [J]. TETRAHEDRON, 1978, 34 (09) : 1389 - 1397
  • [9] Structural aspects of antioxidant activity of flavonoids
    vanAcker, SABE
    vandenBerg, DJ
    Tromp, MNJL
    Griffioen, DH
    VanBennekom, WP
    VanderVijgh, WJF
    Bast, A
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 1996, 20 (03) : 331 - 342
  • [10] Yokozawa T, 1997, PHYTOTHER RES, V11, P446, DOI 10.1002/(SICI)1099-1573(199709)11:6<446::AID-PTR128>3.3.CO